Examined the effectiveness of an evidence-based prevention program implemented on a sample of 715 families across mulitple settings in an urban area. The study area also included suburban Maryland. Was set up as a true experimental design with families being randomly placed into 1 of 4 treatment conditions: child skills training only, parent skills training only, parent and child skills training plus family skills training, or minimal treatment controls. Entire families were assigned to 1 of the 4 treatment conditions. Data were collected from all family members who participated in the program. Thus the individual data files contain more than 715 records. The parent file contains 796 cases and the child file contains 961 cases. The Strengthening Families Program is based on cognitive-behavioral social learning theory and family systems theory targeting elementary school-aged children. In this program parents receive training in parenting skills, children receive training primarily in social skills, and families receive family skills training. The aim of the program is to effectively reduce parent, child, and family risk factors for substance use and delinquency.