Estimates were produced for diphtheria-pertussis-tetanus (DPT) vaccine coverage and dropout for children ages 12-23 months at the 5x5 km-level in 52 countries in Africa between 2000-2016. These estimates were produced using data from 183 population-based household surveys conducted in Africa between 2000 and 2016 that included dose-specific information on DPT coverage (from vaccine cards or maternal recall in the absence of vaccine cards) and subnational geographical location for children ages 12-59 months.