This is a limited dataset from a pilot mobile survey of attitudes and behaviors surrounding COVID-19, including vaccine attitudes, among people experiencing homelessness in Los Angeles, CA. The dataset includes basic demographic data (including age, race, sex, and housing status), COVID-19 protective behaviors, COVID-19 threat perception, trusted news sources, COVID-19 vaccination status and attitudes, and depression status (as measured by PHQ-4). Baseline demographic data was collected in November 2020 - January 2021. Data for variables relating to COVID-19 and depression status was collected February 2021, which was the 3rd wave of monthly data collection from this survey.